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Science Bowl Question

📅 MIT Science Bowl Invitational 2020🎓 HS🔄 Round 12#️⃣ Question 10 TOSS UP📝 Multiple Choice

In order to synthesize ketones directly from acid derivatives, organolithiums and Grignard reagents are often employed. Which of the following acid derivatives would be least likely to generate good yields of ketone when reacted with an organolithium reagent?

W) Carboxylic acid
X) Ester
Y) N-methoxy-N-methylamide
Z) Nitrile
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